BiologicallyderiveddotBiologically Derived

Galatea Surgical Scaffold® is made from P4HB Woman-Scarf-Still A macropourous, monofilament, fully absorbable scaffold with long term strength retention and predictable resorption profile, was elusive in the field of plastic and reconstructive surgery until the development of Galatea scaffolds.

Galatea Surgical is passionate about bringing your patient’s Strength and Beauty to life through reinforcement of weak and compromised tissue by providing innovative solutions for soft tissue support. The Galatea team has created a collection of scaffolds that offer a unique combination of properties utilizing non-cadaveric, non-human, non-animal, non-synthetic, biologically derived fully absorbable material: poly-4-hydroxybutyrate (P4HB) for plastic and reconstructive surgery procedures. P4HB degrades gradually and predictably by hydrolysis into components that are natural to the human body, resulting in a minimal inflammatory response with less acidic byproducts or remodeling challenges, as compared to other soft tissue support devices.

Watch the Galatea Scaffold Collection Overview.

MonofilamentdotMonofilament

 

The monofilament scaffold was designed with an open pore knit pattern to encourage rapid tissue ingrowth and to reduce risk of infection. [3,6,9]

It has been reported that monofilament fibers have on average 60% less surface area than that of multifilament materials, which may improve the healing response.[3,15]

With less surface area, monofilament scaffolds have fewer recesses that bacteria can use as a haven from the body’s natural defense systems or antibiotic treatments.[3,13]

When comparing SEM images of Galatea Scaffolds and other resorbable materials, the open pores, the smooth surface, and the monofilament structure of Galatea scaffolds are clearly visible.

Galatea Surgical Scaffold 20x Seri Scaffold 20x

VICRYL mesh 20x

Galatea Scaffolds
Monofilament derived from P4HB
SEM Photo, 20x
SERI® Scaffold
Multifilament
SEM Photo, 20x
TIGR® Mesh
Multifilament
SEM Photo, 20x
Woven VICRYL® Mesh
Multifilament
SEM Photo, 20x

StrongdotStrong

Galatea surgical scaffolds were designed  specifically for rapid tissue regeneration and strength retention throughout the critical healing period. [1,9,19] In pre-clinical studies this repair resulted in a new tissue plane approximately 3-4 times the strength of native tissue. [9,19]

Galatea scaffold maintains greater than 70% of its strength at 12 weeks in vivo. [2]

As the scaffold bioresorbs, the new ingrown tissue provides strength to the repair site. [19]

By 52 weeks the new ingrown tissue is approximately 2.4 mm thick and provides a majority of strength to the repair site.  [2,23]

By providing a lattice for tissue regeneration, the Galatea scaffold encourages cells to migrate into its pores, allowing stronger, organized collagen to be built and healthy blood vessels to form.[1,16]

By 6 Weeks

New tissue with abundant mature collagen (as indicatedby positive type I collagen staining) and vascularization (as shown by positive CD31 and smooth muscle actin stains) has quickly integrated into the scaffold. [1]

By 7 Months

A fully integrated tissue plane of primarily type I collagen throughout the scaffold indicates collagen maturation and soft tissue regeneration (minimal inflammatory response with no evidence of encapsulation). [1]

BioresorbabledotBioresorbable

Galatea Scaffolds are constructed from P4HB which gradually and predictably bioresorb over the course of 18-24 months.  [2,12] 

The scaffolds are broken down within the body primarily by the process of hydrolysis and ultimately eliminated as CO2 and H2O. [9,12]

As the scaffold bioresorbs, the new ingrown tissue provides strength to the repair site. [19]

No polymer metabolites remain after the degradation process is complete. [2]

Comparative Scaffold Characteristics

Galatea scaffold provides strong support to help you achieve the desired surgical outcome. In comparison to commercially available soft tissue support scaffolds: